EARS2 Antikörper (C-Term)

Produktnummer ABIN391828

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch EARS2 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für EARS2 Antikörper (C-Term) (ABIN391828)

Target: EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EARS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB14808

Produktdetails anti-EARS2 Antikörper

Bindungsspezifität: AA 495-523, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human EARS2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-EARS2 Antikörper (ABIN391828)

Boczonadi, Smith, Pyle, Gomez-Duran, Schara, Tulinius, Chinnery, Horvath: "Altered 2-thiouridylation impairs mitochondrial translation in reversible infantile respiratory chain deficiency." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4602-15, (2013) (PubMed).

Details zu EARS2

Target: EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))

Andere Bezeichnung: EARS2

Hintergrund: Glutamyl-tRNA synthetase (GluRS or EARS2) a class I aminoacyl-tRNA synthetase (aaRS), is primarily responsible for the glutamylation of tRNAGlu. It is part of the ?minimal set?of seventeen aaRSs found in every living organism and its presence is essential for the viability of cells.

Molekulargewicht: 58689

Gen-ID: 124454

NCBI Accession: NP_001077083

UniProt: Q5JPH6